Antioxidant & Oxidant Stress Test

Oxidation is an essential process that helps your body convert food into energy, eliminate toxins, and repair cells. Without oxidation, the body would be unable to function properly. However, excessive oxidation can also be damaging to the body. This is called oxidative stress. This imbalance can lead to cellular damage and various health conditions.

This test is useful for anyone who wants to evaluate their oxidative stress levels, including those with risk factors such as smoking, unbalanced diet, high cholesterol (hyperlipidemia), or a family history of cardiovascular disease.

An abnormal result may indicate an increased risk of developing certain health conditions such as cancer, heart disease, or diabetes. A healthcare provider may recommend dietary or lifestyle changes or further testing to rule out or confirm potential health risks or disorders.

No doctor’s visit needed.

When the body is exposed to stressors like tobacco smoke, unbalanced diet, pollution, or ultraviolet radiation, it can produce compounds known as F2-isoprostanes. These compounds can contribute to cell damage and the development of various diseases.


F2-isoprostanes are compounds formed from arachidonic acid, an essential fatty acid. Arachidonic acid is found in cell membranes and is used to create various hormones and signaling molecules. The body can create arachidonic acid from other fats, but it can also be obtained through foods, such as egg yolks and red meat. When consumed, arachidonic acid is first broken down into smaller molecules before being used by the body. Once broken down, arachidonic acid can be used to create various signaling molecules that play a role in inflammation and blood clotting. Although the body needs arachidonic acid to function properly, too much of it can increase the production of F2-isoprostane which can damage the body’s tissues and therefore contribute to heart disease and stroke and the onset of chronic disease.


F2-isoprostane levels are an important marker of oxidative stress, and so it is essential to account for variations in urine dilution when measuring them. Urinary creatinine is a waste product of muscle metabolism. Creatinine is transported through the bloodstream to the kidneys, where it is filtered and eliminated from the body through urine.


Urinary creatinine is generally used as a marker of kidney function and to correct for urinary dilution or variations. As such, accounting for urinary creatinine levels is essential to obtain an accurate measure of F2-isoprostanes.

What's Included

Common Questions